Polymeric nanoparticles containing kojic acid induce structural alterations and apoptosis-like death in Leishmania (Leishmania) amazonensis

Polymeric nanoparticles containing kojic acid induce structural alterations and apoptosis-like death in Leishmania (Leishmania) amazonensis

Leishmaniasis encompasses a cluster of neglected tropical diseases triggered by kinetoplastid phatogens belonging to the genus Leishmania. Current therapeutic approaches are toxic, expensive, and require long-term treatment. Nanoparticles are emerging as a new alternative for the treatment of neglec...

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Bibliographic Details
Main Authors: Poliana Queiroz-Souza, Adan Galue-Parra, Lienne Silveira Moraes, Caroline Gomes Macedo, Ana Paula Drummond Rodrigues, Victor H. S. Marinho, Fabricio H. Holanda, Irlon M. Ferreira, Edilene Oliveira da Silva
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-01-01
Series:Frontiers in Pharmacology
Subjects:
leishmanicidal activity
nanoparticle
kojic acid
silk fibroin
drug delivery system
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2024.1331240/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2024.1331240/full

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