Detection of N-glycolyl-neuraminic acid-containing glycolipids in human skin

Humans lack the enzyme that produces the sialic acid N-glycolyl neuraminic acid (Neu5Gc), but several lines of evidence have shown that Neu5Gc can be taken up by mammalian food sources and replace the common human sialic acid N-acetyl neuraminic acid (Neu5Ac) in glycans. Cancer tissue has been shown...

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Bibliographic Details
Main Authors: Michela Manni, Natalia Rodrigues Mantuano, Andreas Zingg, Elisabeth A. Kappos, Anna-Janina Behrens, Jonathan Back, Rainer Follador, Amir Faridmoayer, Heinz Läubli
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-11-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1291292/full