Development of an anti‐BAG3 humanized antibody for treatment of pancreatic cancer

Development of an anti‐BAG3 humanized antibody for treatment of pancreatic cancer

We have previously shown that secreted BAG3 is a potential target for the treatment of pancreatic ductal adenocarcinoma and that pancreatic tumor growth and metastatic dissemination can be reduced by treatment with an anti‐BAG3 murine antibody. Here, we used complementarity‐determining region (CDR)...

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Bibliographic Details
Main Authors: Anna Basile, Margot De Marco, Michelina Festa, Antonia Falco, Vittoria Iorio, Luana Guerriero, Daniela Eletto, Domenica Rea, Claudio Arra, Alessia Lamolinara, Patrizia Ballerini, Verena Damiani, Alessandra Rosati, Gianluca Sala, Maria Caterina Turco, Liberato Marzullo, Vincenzo De Laurenzi
Format: Article
Language:English
Published: Wiley 2019-06-01
Series:Molecular Oncology
Subjects:
BAG3
humanized antibody
pancreatic cancer
pancreatic ductal adenocarcinoma
tumor therapy
Online Access:https://doi.org/10.1002/1878-0261.12492

Internet

https://doi.org/10.1002/1878-0261.12492

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