Synovial monocytes contribute to chronic inflammation in childhood-onset arthritis via IL-6/STAT signalling and cell-cell interactions

Synovial monocytes contribute to chronic inflammation in childhood-onset arthritis via IL-6/STAT signalling and cell-cell interactions

IntroductionMonocytes are key effector cells in inflammatory processes. We and others have previously shown that synovial monocytes in childhood-onset arthritis are activated. However, very little is known about how they contribute to disease and attain their pathological features. Therefore, we set...

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Bibliographic Details
Main Authors: Tobias Schmidt, Alma Dahlberg, Elisabet Berthold, Petra Król, Sabine Arve-Butler, Emilia Rydén, Seyed Morteza Najibi, Anki Mossberg, Anders A. Bengtsson, Fredrik Kahn, Bengt Månsson, Robin Kahn
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-05-01
Series:Frontiers in Immunology
Subjects:
monocyte
inflammation
juvenile idiopathic arthritis – JIA
synovial fluid (SF)
IL-6
rheumatology
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1190018/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2023.1190018/full

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