Underlying pharmacological mechanisms of psilocin-induced broadband desynchronization and disconnection of EEG in rats

Underlying pharmacological mechanisms of psilocin-induced broadband desynchronization and disconnection of EEG in rats

IntroductionPsilocybin is one of the most extensively studied psychedelic drugs with a broad therapeutic potential. Despite the fact that its psychoactivity is mainly attributed to the agonism at 5-HT2A receptors, it has high binding affinity also to 5-HT2C and 5-HT1A receptors and indirectly modula...

Full description

Bibliographic Details
Main Authors: Filip Tylš, Čestmír Vejmola, Vlastimil Koudelka, Václava Piorecká, Lukáš Kadeřábek, Marcel Bochin, Tomáš Novák, Martin Kuchař, Zdeňka Bendová, Martin Brunovský, Jiří Horáček, Tomáš Pálení ček
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-06-01
Series:Frontiers in Neuroscience
Subjects:
serotonergic psychedelics
psilocybin/psilocin
model of acute psychosis
quantitative EEG
power spectra
phase-lagged coherence
Online Access:https://www.frontiersin.org/articles/10.3389/fnins.2023.1152578/full

Internet

https://www.frontiersin.org/articles/10.3389/fnins.2023.1152578/full

Similar Items