Underlying pharmacological mechanisms of psilocin-induced broadband desynchronization and disconnection of EEG in rats

Underlying pharmacological mechanisms of psilocin-induced broadband desynchronization and disconnection of EEG in rats

IntroductionPsilocybin is one of the most extensively studied psychedelic drugs with a broad therapeutic potential. Despite the fact that its psychoactivity is mainly attributed to the agonism at 5-HT2A receptors, it has high binding affinity also to 5-HT2C and 5-HT1A receptors and indirectly modula...

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Main Authors:	Filip Tylš, Čestmír Vejmola, Vlastimil Koudelka, Václava Piorecká, Lukáš Kadeřábek, Marcel Bochin, Tomáš Novák, Martin Kuchař, Zdeňka Bendová, Martin Brunovský, Jiří Horáček, Tomáš Pálení ček
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2023-06-01
Series:	Frontiers in Neuroscience
Subjects:	serotonergic psychedelics psilocybin/psilocin model of acute psychosis quantitative EEG power spectra phase-lagged coherence
Online Access:	https://www.frontiersin.org/articles/10.3389/fnins.2023.1152578/full

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