Medial Collagen Type and Quantity Influence Mechanical Properties of Aneurysm Wall in Bicuspid Aortic Valve Patients

Medial Collagen Type and Quantity Influence Mechanical Properties of Aneurysm Wall in Bicuspid Aortic Valve Patients

Collagen has an essential role in aortic biomechanics, and collagen remodeling has been associated with the development and progression of aortic aneurysm. However, the exact mechanisms behind collagen remodeling and the biomechanical implications are not well understood. This study presents an inve...

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Bibliographic Details
Main Authors: Louise Neave, Maria Tahir, Miriam Nightingale, Anshul S. Jadli, Vaibhav B. Patel, Alexander J. Barker, S. Chris Malaisrie, Patrick M. McCarthy, Michael Markl, Paul W. M. Fedak, Elena S. Di Martino
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-06-01
Series:Frontiers in Mechanical Engineering
Subjects:
collagen remodeling
aortic aneurysm
bicuspid aortic valve
tissue biomechanics
extracellular matrix
Online Access:https://www.frontiersin.org/articles/10.3389/fmech.2022.874243/full

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https://www.frontiersin.org/articles/10.3389/fmech.2022.874243/full

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