Self-Renewing Human Bone Marrow Mesenspheres Promote Hematopoietic Stem Cell Expansion

Self-Renewing Human Bone Marrow Mesenspheres Promote Hematopoietic Stem Cell Expansion

Strategies for expanding hematopoietic stem cells (HSCs) include coculture with cells that recapitulate their natural microenvironment, such as bone marrow stromal stem/progenitor cells (BMSCs). Plastic-adherent BMSCs may be insufficient to preserve primitive HSCs. Here, we describe a method of isol...

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Bibliographic Details
Main Authors: Joan Isern, Beatriz Martín-Antonio, Roshanak Ghazanfari, Ana M. Martín, Juan A. López, Raquel del Toro, Abel Sánchez-Aguilera, Lorena Arranz, Daniel Martín-Pérez, María Suárez-Lledó, Pedro Marín, Melissa Van Pel, Willem E. Fibbe, Jesús Vázquez, Stefan Scheding, Álvaro Urbano-Ispizúa, Simón Méndez-Ferrer
Format: Article
Language:English
Published: Elsevier 2013-05-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124713001654

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http://www.sciencedirect.com/science/article/pii/S2211124713001654

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