MAGMA: generalized gene-set analysis of GWAS data.

By aggregating data for complex traits in a biologically meaningful way, gene and gene-set analysis constitute a valuable addition to single-marker analysis. However, although various methods for gene and gene-set analysis currently exist, they generally suffer from a number of issues. Statistical p...

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Bibliographic Details
Main Authors: Christiaan A de Leeuw, Joris M Mooij, Tom Heskes, Danielle Posthuma
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-04-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC4401657?pdf=render