Uncovering Pharmacological Opportunities for Cancer Stem Cells—A Systems Biology View

Uncovering Pharmacological Opportunities for Cancer Stem Cells—A Systems Biology View

Cancer stem cells (CSCs) represent a small fraction of the total cancer cell population, yet they are thought to drive disease propagation, therapy resistance and relapse. Like healthy stem cells, CSCs possess the ability to self-renew and differentiate. These stemness phenotypes of CSCs rely on mul...

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Bibliographic Details
Main Authors: Cristina Correia, Taylor M Weiskittel, Choong Yong Ung, Jose C Villasboas Bisneto, Daniel D Billadeau, Scott H Kaufmann, Hu Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-03-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
cancer stem cells
cellular niche
tumor microenvironment
systems biology
immunotherapy
drug resistance
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2022.752326/full

Internet

https://www.frontiersin.org/articles/10.3389/fcell.2022.752326/full

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