Copy-back viral genomes induce a cellular stress response that interferes with viral protein expression without affecting antiviral immunity.

Antiviral responses are often accompanied by translation inhibition and formation of stress granules (SGs) in infected cells. However, the triggers for these processes and their role during infection remain subjects of active investigation. Copy-back viral genomes (cbVGs) are the primary inducers of...

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Bibliographic Details
Main Authors: Lavinia J González Aparicio, Yanling Yang, Matthew Hackbart, Carolina B López
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2023-11-01
Series:PLoS Biology
Online Access:https://journals.plos.org/plosbiology/article/file?id=10.1371/journal.pbio.3002381&type=printable