Spliceosome inhibitor induces human hematopoietic progenitor cell reprogramming toward stemness

Abstract The application of hematopoietic stem cells (HSCs) has been restricted due to limited cell sources and conventional methods for generating these cells by cell expansion and pluripotent stem cell differentiation have not been clinically achieved. Cell reprogramming technique provides a new h...

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Bibliographic Details
Main Authors: Liaoliao Dong, Chuijin Wei, Shumin Xiong, Ping Yu, Ren Zhou, Lin Cheng
Format: Article
Language:English
Published: BMC 2022-06-01
Series:Experimental Hematology & Oncology
Subjects:
Online Access:https://doi.org/10.1186/s40164-022-00288-9