The impact of realistic axonal shape on axon diameter estimation using diffusion MRI

To study axonal microstructure with diffusion MRI, axons are typically modeled as straight impermeable cylinders, whereby the transverse diffusion MRI signal can be made sensitive to the cylinder’s inner diameter. However, the shape of a real axon varies along the axon direction, which couples the l...

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Bibliographic Details
Main Authors: Hong-Hsi Lee, Sune N. Jespersen, Els Fieremans, Dmitry S. Novikov
Format: Article
Language:English
Published: Elsevier 2020-12-01
Series:NeuroImage
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S105381192030714X