Relationship between drug holiday of the antiresorptive agents and surgical outcome of medication-related osteonecrosis of the jaw in osteoporosis patients

Abstract A drug holiday of 3 months does not promote separation of sequestra and is not correlated with treatment outcomes after surgical therapy in osteoporosis patients who receive antiresorptive agents and who have medication-related osteonecrosis of the jaw. Medication-related osteonecrosis of t...

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Bibliographic Details
Main Authors: Kota Morishita, Sakiko Soutome, Mitsunobu Otsuru, Saki Hayashida, Maho Murata, Miho Sasaki, Yukinori Takagi, Misa Sumi, Masahiro Umeda
Format: Article
Language:English
Published: Nature Portfolio 2022-07-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-15720-7