Deconvolution at the single-cell level reveals ovarian cell-type-specific transcriptomic changes in PCOS

Deconvolution at the single-cell level reveals ovarian cell-type-specific transcriptomic changes in PCOS

Abstract Background Polycystic ovary syndrome (PCOS) is one of the most common reproductive endocrine disorders in females of childbearing age. Various types of ovarian cells work together to maintain normal reproductive function, whose discordance often takes part in the development and progression...

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Bibliographic Details
Main Authors: Shumin Li, Yimeng Li, Yu Sun, Gengchen Feng, Ziyi Yang, Xueqi Yan, Xueying Gao, Yonghui Jiang, Yanzhi Du, Shigang Zhao, Han Zhao, Zi-Jiang Chen
Format: Article
Language:English
Published: BMC 2024-02-01
Series:Reproductive Biology and Endocrinology
Subjects:
Polycystic ovary syndrome
Deconvolution
Granulosa cells
scRNA-seq
Bulk RNA-seq
Online Access:https://doi.org/10.1186/s12958-024-01195-w

Internet

https://doi.org/10.1186/s12958-024-01195-w

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