Exploring the depths of IgG4: insights into autoimmunity and novel treatments

IgG4 subclass antibodies represent the rarest subclass of IgG antibodies, comprising only 3-5% of antibodies circulating in the bloodstream. These antibodies possess unique structural features, notably their ability to undergo a process known as fragment-antigen binding (Fab)-arm exchange, wherein t...

Full description

Bibliographic Details
Main Authors: Selen Ünlü, Blanca G. Sánchez Navarro, Elif Cakan, Daniel Berchtold, Rafael Meleka Hanna, Secil Vural, Atay Vural, Andreas Meisel, Miriam L. Fichtner
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-04-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1346671/full