Co-chaperone involvement in knob biogenesis implicates host-derived chaperones in malaria virulence.

The pathology associated with malaria infection is largely due to the ability of infected human RBCs to adhere to a number of receptors on endothelial cells within tissues and organs. This phenomenon is driven by the export of parasite-encoded proteins to the host cell, the exact function of many of...

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Bibliographic Details
Main Authors: Mathias Diehl, Lena Roling, Lukas Rohland, Sebastian Weber, Marek Cyrklaff, Cecilia P Sanchez, Carlo A Beretta, Caroline S Simon, Julien Guizetti, Julia Hahn, Norma Schulz, Matthias P Mayer, Jude M Przyborski
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-10-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1009969