Prostaglandin E2-EP1 and EP2 receptor signaling promotes apical junctional complex disassembly of Caco-2 human colorectal cancer cells

<p>Abstract</p> <p>Background</p> <p>The apical junctional complex (AJC) is a dynamic structure responsible to maintain epithelial cell-cell adhesions and it plays important functions such as, polarity, mechanical integrity, and cell signaling. Alteration of this comple...

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Bibliographic Details
Main Authors: Morgado-Diaz Jose A, de Souza Wanderley, Diaz Bruno L, Tanaka Marcelo N
Format: Article
Language:English
Published: BMC 2008-12-01
Series:BMC Cell Biology
Online Access:http://www.biomedcentral.com/1471-2121/9/63