In Silico Screening of Isocitrate Lyase for Novel Anti-Buruli Ulcer Natural Products Originating from Africa

In Silico Screening of Isocitrate Lyase for Novel Anti-Buruli Ulcer Natural Products Originating from Africa

Buruli ulcer (BU) is caused by Mycobacterium ulcerans and is predominant in both tropical and subtropical regions. The neglected debilitating disease is characterized by chronic necrotizing skin lesions attributed to a mycolactone, which is a macrolide toxin secreted by M. ulcerans. The preferred tr...

Full description

Bibliographic Details
Main Authors: Samuel K. Kwofie, Bismark Dankwa, Emmanuel A. Odame, Francis E. Agamah, Lady P. A. Doe, Joshua Teye, Odame Agyapong, Whelton A. Miller, Lydia Mosi, Michael D. Wilson
Format: Article
Language:English
Published: MDPI AG 2018-06-01
Series:Molecules
Subjects:
virtual screening
homology modeling
buruli ulcer
Mycobacterium ulcerans
molecular dynamics
natural product
Online Access:http://www.mdpi.com/1420-3049/23/7/1550

Internet

http://www.mdpi.com/1420-3049/23/7/1550

Similar Items