<it>Topoisomerase II alpha </it>gene copy loss has adverse prognostic significance in <it>ERBB2</it>-amplified breast cancer: a retrospective study of paraffin-embedded tumor specimens and medical charts

<it>Topoisomerase II alpha </it>gene copy loss has adverse prognostic significance in <it>ERBB2</it>-amplified breast cancer: a retrospective study of paraffin-embedded tumor specimens and medical charts

<p>Abstract</p> <p>Background</p> <p>Amplification of the <it>ERBB2 </it>(<it>Her-2/neu</it>) oncogene, which occurs in approximately 25% of breast carcinomas, is a known negative prognostic factor. Available data indicate that a variable number...

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Bibliographic Details
Main Authors: Zhu April, Jacobson Kris, Rao Ruta D, Morrison Larry E, Tabesh Bita, Usha Lydia, Basu Sanjib, Coon John S
Format: Article
Language:English
Published: BMC 2008-08-01
Series:Journal of Hematology & Oncology
Online Access:http://www.jhoonline.org/content/1/1/12

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http://www.jhoonline.org/content/1/1/12

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