Surface Hydration Protects Cystic Fibrosis Airways from Infection by Restoring Junctional Networks

Surface Hydration Protects Cystic Fibrosis Airways from Infection by Restoring Junctional Networks

Defective hydration of airway surface mucosa is associated with recurrent lung infection in cystic fibrosis (CF), a disease caused by CF transmembrane conductance regulator (<i>CFTR</i>) gene mutations. Whether the composition and/or presence of an airway surface liquid (ASL) is sufficie...

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Bibliographic Details
Main Authors: Juliette L. Simonin, Alexandre Luscher, Davide Losa, Mehdi Badaoui, Christian van Delden, Thilo Köhler, Marc Chanson
Format: Article
Language:English
Published: MDPI AG 2022-05-01
Series:Cells
Subjects:
mucosal immunity
<i>P. aeruginosa</i>
airway surface liquid
epithelium integrity
cystic fibrosis
Online Access:https://www.mdpi.com/2073-4409/11/9/1587

Internet

https://www.mdpi.com/2073-4409/11/9/1587

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