NLRP7 Promotes Choriocarcinoma Growth and Progression through the Establishment of an Immunosuppressive Microenvironment

NLRP7 Promotes Choriocarcinoma Growth and Progression through the Establishment of an Immunosuppressive Microenvironment

The inflammatory gene <i>NLRP7</i> is the major gene responsible for recurrent complete hydatidiform moles (CHM), an abnormal pregnancy that can develop into gestational choriocarcinoma (CC). However, the role of NLRP7 in the development and immune tolerance of CC has not been investigat...

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Bibliographic Details
Main Authors: Deborah Reynaud, Roland Abi Nahed, Nicolas Lemaitre, Pierre-Adrien Bolze, Wael Traboulsi, Frederic Sergent, Christophe Battail, Odile Filhol, Vincent Sapin, Houssine Boufettal, Pascale Hoffmann, Touria Aboussaouira, Padma Murthi, Rima Slim, Mohamed Benharouga, Nadia Alfaidy
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Cancers
Subjects:
choriocarcinoma
hydatidiform mole
NLRP7
tumor microenvironment
maternal immune tolerance
orthotopic model of choriocarcinoma
Online Access:https://www.mdpi.com/2072-6694/13/12/2999

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https://www.mdpi.com/2072-6694/13/12/2999

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