Alveolar–Capillary Barrier Protection In Vitro: Lung Cell Type-Specific Effects and Molecular Mechanisms Induced by 1α, 25-Dihydroxyvitamin D3

Alveolar–Capillary Barrier Protection In Vitro: Lung Cell Type-Specific Effects and Molecular Mechanisms Induced by 1α, 25-Dihydroxyvitamin D3

Low serum levels of 1α, 25-dihydroxyvitamin D3 (VD3) are associated with a higher mortality in trauma patients with sepsis or ARDS. However, the molecular mechanisms behind this observation are not yet understood. VD<sub>3</sub> is known to stimulate lung maturity, alveolar type II cell...

Full description

Bibliographic Details
Main Authors: Junyu Xiong, Patrick Kaleja, Larissa Ückert, Niloufar Nezaratizadeh, Stefanie Krantz, Martin Friedrich Krause, Stefanie Fitschen-Oestern, Andreas Seekamp, Liam Cassidy, Andreas Tholey, Sabine Fuchs
Format: Article
Language:English
Published: MDPI AG 2023-04-01
Series:International Journal of Molecular Sciences
Subjects:
VD3
lung barrier
alveolar epithelial cells
co-culture
LPS
DCLK1
Online Access:https://www.mdpi.com/1422-0067/24/8/7298

Internet

https://www.mdpi.com/1422-0067/24/8/7298

Similar Items