A tool for nuclear imaging of the SARS-CoV-2 entry receptor: molecular model and preclinical development of ACE2-selective radiopeptides

A tool for nuclear imaging of the SARS-CoV-2 entry receptor: molecular model and preclinical development of ACE2-selective radiopeptides

Abstract Purpose The angiotensin converting enzyme-2 (ACE2)—entry receptor of SARS-CoV-2—and its homologue, the angiotensin-converting enzyme (ACE), play a pivotal role in maintaining cardiovascular homeostasis. Potential changes in ACE2 expression levels and dynamics after SARS-CoV-2 infection have...

Full description

Bibliographic Details
Main Authors: Darja Beyer, Christian Vaccarin, Xavier Deupi, Ana Katrina Mapanao, Susan Cohrs, Fan Sozzi-Guo, Pascal V. Grundler, Nicholas P. van der Meulen, Jinling Wang, Matthias Tanriver, Jeffrey W. Bode, Roger Schibli, Cristina Müller
Format: Article
Language:English
Published: SpringerOpen 2023-04-01
Series:EJNMMI Research
Subjects:
DX600
Radiopeptide
Gallium
PET
ACE2
ACE
Online Access:https://doi.org/10.1186/s13550-023-00979-2

Internet

https://doi.org/10.1186/s13550-023-00979-2

Similar Items