Brain-derived neurotrophic factor serum levels following ketamine and esketamine intervention for treatment-resistant depression: secondary analysis from a randomized trial

Brain-derived neurotrophic factor serum levels following ketamine and esketamine intervention for treatment-resistant depression: secondary analysis from a randomized trial

Abstract Objectives Evidence suggests that ketamine’s influence on brain-derived neurotrophic factor (BDNF) might be involved in its mechanism of rapid antidepressant action. We aimed to evaluate the differential impact of ketamine and esketamine on serum BDNF levels and its association with respo...

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Bibliographic Details
Main Authors: Ana Teresa Caliman-Fontes, Gustavo C. Leal, Fernanda S. Correia-Melo, Camilla S. Paixao, Michelle S. Carvalho, Ana Paula Jesus-Nunes, Flavia Vieira, Guilherme Magnavita, Igor D. Bandeira, Rodrigo P. Mello, Graziele Beanes, Samantha S. Silva, Mariana Echegaray, Lucas P. Carvalho, Paulo Machado, Aline S. Sampaio, Taiane de A. Cardoso, Flávio Kapczinski, Acioly L. T. Lacerda, Lucas C. Quarantini
Format: Article
Language:English
Published: Associação de Psiquiatria do Rio Grande do Sul 2023-02-01
Series:Trends in Psychiatry and Psychotherapy
Subjects:
BDNF
biochemical markers
major depressive disorder
NMDA antagonists
neurotrophins
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S2237-60892023000100405&lng=en&tlng=en

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S2237-60892023000100405&lng=en&tlng=en

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