Streamlined Subpopulation, Subtype, and Recombination Analysis of HIV-1 Half-Genome Sequences Generated by High-Throughput Sequencing

Streamlined Subpopulation, Subtype, and Recombination Analysis of HIV-1 Half-Genome Sequences Generated by High-Throughput Sequencing

ABSTRACT High-throughput sequencing (HTS) has been widely used to characterize HIV-1 genome sequences. There are no algorithms currently that can directly determine genotype and quasispecies population using short HTS reads generated from long genome sequences without additional software. To establi...

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Bibliographic Details
Main Authors: Bhavna Hora, Naila Gulzar, Yue Chen, Konstantinos Karagiannis, Fangping Cai, Chang Su, Krista Smith, Vahan Simonyan, Sharaf Ali Shah, Manzoor Ahmed, Ana M. Sanchez, Mars Stone, Myron S. Cohen, Thomas N. Denny, Raja Mazumder, Feng Gao
Format: Article
Language:English
Published: American Society for Microbiology 2020-10-01
Series:mSphere
Subjects:
HIV-1
genetic recombination
quasispecies
sequencing
Online Access:https://journals.asm.org/doi/10.1128/mSphere.00551-20

Internet

https://journals.asm.org/doi/10.1128/mSphere.00551-20

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