Could the Urease of the Gut Bacterium <i>Proteus mirabilis</i> Play a Role in the Altered Gut–Brain Talk Associated with Parkinson’s Disease?

Could the Urease of the Gut Bacterium <i>Proteus mirabilis</i> Play a Role in the Altered Gut–Brain Talk Associated with Parkinson’s Disease?

Intestinal dysbiosis seems to play a role in neurodegenerative pathologies. Parkinson’s disease (PD) patients have an altered gut microbiota. Moreover, mice treated orally with the gut microbe <i>Proteus mirabilis</i> developed Parkinson’s-like symptoms. Here, the possible involvement of...

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Bibliographic Details
Main Authors: Matheus V. C. Grahl, Brenda da Silva Andrade, Ana Paula A. Perin, Gilda A. Neves, Laura de Souza Duarte, Augusto Frantz Uberti, Kelvin Siqueira Hohl, Cristian Follmer, Celia Regina Carlini
Format: Article
Language:English
Published: MDPI AG 2023-08-01
Series:Microorganisms
Subjects:
neuroinflammation
α-synucleinopathies
Parkinson’s disease
bacterial ureases
behavioral analysis
motor deficits
Online Access:https://www.mdpi.com/2076-2607/11/8/2042

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https://www.mdpi.com/2076-2607/11/8/2042

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