Cardamonin suppresses pro-tumor function of macrophages by decreasing M2 polarization on ovarian cancer cells via mTOR inhibition

Cardamonin suppresses pro-tumor function of macrophages by decreasing M2 polarization on ovarian cancer cells via mTOR inhibition

Ovarian cancer is the most fatal tumor characterized by an abundance of tumor-associated macrophage (TAM) infiltrations in women. Functional TAMs, which mainly present M2-like phenotypes and perform key functions on tumor progress, have been considered an attractive target for ovarian cancer therapy...

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Bibliographic Details
Main Authors: Huajiao Chen, Sheng Huang, Peiguang Niu, Yanting Zhu, Jintuo Zhou, Li Jiang, Danyun Li, Daohua Shi
Format: Article
Language:English
Published: Elsevier 2022-09-01
Series:Molecular Therapy: Oncolytics
Subjects:
cardamonin
TAMs
mTOR
STAT3
ovarian cancer
Online Access:http://www.sciencedirect.com/science/article/pii/S2372770522000894

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http://www.sciencedirect.com/science/article/pii/S2372770522000894

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