<i>Candida albicans</i> Genes Modulating Echinocandin Susceptibility of Caspofungin-Adapted Mutants Are Constitutively Expressed in Clinical Isolates with Intermediate or Full Resistance to Echinocandins

<i>Candida albicans</i> Genes Modulating Echinocandin Susceptibility of Caspofungin-Adapted Mutants Are Constitutively Expressed in Clinical Isolates with Intermediate or Full Resistance to Echinocandins

The opportunistic fungus <i>Candida albicans</i> is the leading cause of invasive candidiasis in immune-compromised individuals. Drugs from the echinocandin (ECN) class, including caspofungin, are used as a first line of therapy against invasive candidiasis. The only known mechanism of c...

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Bibliographic Details
Main Authors: Anshuman Yadav, Sudisht K. Sah, David S. Perlin, Elena Rustchenko
Format: Article
Language:English
Published: MDPI AG 2024-03-01
Series:Journal of Fungi
Subjects:
<i>Candida albicans</i>
echinocandin susceptibility
drug adaptation
clinical isolates
Online Access:https://www.mdpi.com/2309-608X/10/3/224

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https://www.mdpi.com/2309-608X/10/3/224

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