Characterization of a Bioactive Peptide T14 in the Human and Rodent Substantia Nigra: Implications for Neurodegenerative Disease

Characterization of a Bioactive Peptide T14 in the Human and Rodent Substantia Nigra: Implications for Neurodegenerative Disease

The substantia nigra is generally considered to show significant cell loss not only in Parkinson’s but also in Alzheimer’s disease, conditions that share several neuropathological traits. An interesting feature of this nucleus is that the pars compacta dopaminergic neurons contain acetylcholinestera...

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Bibliographic Details
Main Authors: Susan Adele Greenfield, Giovanni Ferrati, Clive W. Coen, Auguste Vadisiute, Zoltan Molnár, Sara Garcia-Rates, Sally Frautschy, Gregory M. Cole
Format: Article
Language:English
Published: MDPI AG 2022-10-01
Series:International Journal of Molecular Sciences
Subjects:
acetylcholinesterase
T14
NBP14
dopamine
substantia nigra
Alzheimer’s disease
Online Access:https://www.mdpi.com/1422-0067/23/21/13119

Internet

https://www.mdpi.com/1422-0067/23/21/13119

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