Enhanced Aβ(1-40) production in endothelial cells stimulated with fibrillar Aβ(1-42).

Enhanced Aβ(1-40) production in endothelial cells stimulated with fibrillar Aβ(1-42).

Amyloid accumulation in the brain of Alzheimer's patients results from altered processing of the 39- to 43-amino acid amyloid β protein (Aβ). The mechanisms for the elevated amyloid (Aβ(1-42)) are considered to be over-expression of the amyloid precursor protein (APP), enhanced cleavage of APP...

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Main Authors: Jayakumar Rajadas, Wenchao Sun, Hai Li, Mohammed Inayathullah, Damiano Cereghetti, Aaron Tan, Valeria de Mello Coelho, Francis J Chrest, John W Kusiak, Wanli Wei Smith, Dennis Taub, Joseph C Wu, Joseph M Rifkind
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3591408?pdf=render

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http://europepmc.org/articles/PMC3591408?pdf=render

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