Postsynaptic burst reactivation of hippocampal neurons enables associative plasticity of temporally discontiguous inputs

A fundamental unresolved problem in neuroscience is how the brain associates in memory events that are separated in time. Here, we propose that reactivation-induced synaptic plasticity can solve this problem. Previously, we reported that the reinforcement signal dopamine converts hippocampal spike t...

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Bibliographic Details
Main Authors: Tanja Fuchsberger, Claudia Clopath, Przemyslaw Jarzebowski, Zuzanna Brzosko, Hongbing Wang, Ole Paulsen
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2022-10-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/81071