Mechanoregulation of Osteoclastogenesis-Inducing Potentials of Fibrosarcoma Cell Line by Substrate Stiffness

Mechanoregulation of Osteoclastogenesis-Inducing Potentials of Fibrosarcoma Cell Line by Substrate Stiffness

A micro-physiological system is generally fabricated using soft materials, such as polydimethylsiloxane silicone (PDMS), and seeks an inflammatory osteolysis model for osteoimmunological research as one of the development needs. Microenvironmental stiffness regulates various cellular functions via m...

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Bibliographic Details
Main Authors: Watcharaphol Tiskratok, Masahiro Yamada, Jun Watanabe, Qu Pengyu, Tsuyoshi Kimura, Hiroshi Egusa
Format: Article
Language:English
Published: MDPI AG 2023-05-01
Series:International Journal of Molecular Sciences
Subjects:
cellular mechanotransduction
extracellular matrix
micro-physiological system
osteoclastogenesis
proinflammatory mediator
Online Access:https://www.mdpi.com/1422-0067/24/10/8959

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https://www.mdpi.com/1422-0067/24/10/8959

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