Omicron-included mutation-induced changes in epitopes of SARS-CoV-2 spike protein and effectiveness assessments of current antibodies

Abstract The COVID-19 pandemic, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is spreading globally and continues to rage, posing a serious threat to human health and life quality. Antibody therapy and vaccines both have shown great efficacy in the prevention and treatment...

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Bibliographic Details
Main Authors: Du Guo, Huaichuan Duan, Yan Cheng, Yueteng Wang, Jianping Hu, Hubing Shi
Format: Article
Language:English
Published: Springer 2022-04-01
Series:Molecular Biomedicine
Subjects:
Online Access:https://doi.org/10.1186/s43556-022-00074-3