EXOME SEQUENCING REVEALS PRIMARY IMMUNODEFICIENCIES IN CHILDREN WITH COMMUNITY-ACQUIRED PSEUDOMONAS AERUGINOSA SEPSIS

EXOME SEQUENCING REVEALS PRIMARY IMMUNODEFICIENCIES IN CHILDREN WITH COMMUNITY-ACQUIRED PSEUDOMONAS AERUGINOSA SEPSIS

One out of three pediatric sepsis deaths in high income countries occur in previously healthy children. Primary immunodeficiencies have been postulated to underlie fulminant sepsis, but this concept remains to be confirmed in clinical practice. Pseudomonas aeruginosa (P. aeruginosa) is a common bact...

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Bibliographic Details
Main Authors: Samira Asgari, Paul McLaren, Jane Peake, Melanie Wong, Richard Wong, Joshua R Francis, Katia Abarca, Kyra A Gelderman, Philipp Agyeman, Christoph Aebi, Christoph Berger, Jacques Fellay, Luregn J Schlapbach
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-09-01
Series:Frontiers in Immunology
Subjects:
Bacteremia
Pseudomonas
Sepsis
immunodeficiency
exome sequencing
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2016.00357/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fimmu.2016.00357/full

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