Antifibrotic Mechanism of Piceatannol in Bleomycin-Induced Pulmonary Fibrosis in Mice

Antifibrotic Mechanism of Piceatannol in Bleomycin-Induced Pulmonary Fibrosis in Mice

Background: Idiopathic pulmonary fibrosis (IPF) is a progressive and fatal interstitial lung disease characterized by myofibroblast accumulation and extracellular matrix deposition, which lead to irreversible damage of the lung’s architecture and the formation of fibrotic lesions. IPF is also a sequ...

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Bibliographic Details
Main Authors: Hanjing Sheng, Gang Lin, Shengxian Zhao, Weibin Li, Zhaolin Zhang, Weidong Zhang, Li Yun, Xiaoyang Yan, Hongyu Hu
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-06-01
Series:Frontiers in Pharmacology
Subjects:
autophagy
TGF-β1
myofibroblasts
pulmonary fibrosis
piceatannol
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2022.771031/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2022.771031/full

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