Advanced EPI-X4 Derivatives Covalently Bind Human Serum Albumin Resulting in Prolonged Plasma Stability

Advanced EPI-X4 Derivatives Covalently Bind Human Serum Albumin Resulting in Prolonged Plasma Stability

Advanced derivatives of the <b>E</b>ndogenous <b>P</b>eptide <b>I</b>nhibitor of C<b>X</b>CR<b>4</b> (EPI-X4) have shown therapeutic efficacy upon topical administration in animal models of asthma and dermatitis. Here, we studied the plasma...

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Bibliographic Details
Main Authors: Armando Rodríguez-Alfonso, Astrid Heck, Yasser Bruno Ruiz-Blanco, Andrea Gilg, Ludger Ständker, Seah Ling Kuan, Tanja Weil, Elsa Sanchez-Garcia, Sebastian Wiese, Jan Münch, Mirja Harms
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:International Journal of Molecular Sciences
Subjects:
EPI-X4
albumin carrier
peptide stability
CXCR4 antagonist
Online Access:https://www.mdpi.com/1422-0067/23/23/15029

Internet

https://www.mdpi.com/1422-0067/23/23/15029

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