Infection of the maternal-fetal interface and vertical transmission following low-dose inoculation of pregnant rhesus macaques (Macaca mulatta) with an African-lineage Zika virus.

Infection of the maternal-fetal interface and vertical transmission following low-dose inoculation of pregnant rhesus macaques (Macaca mulatta) with an African-lineage Zika virus.

<h4>Background</h4>Congenital Zika virus (ZIKV) infection can result in birth defects, including malformations in the fetal brain and visual system. There are two distinct genetic lineages of ZIKV: African and Asian. Asian-lineage ZIKVs have been associated with adverse pregnancy outcome...

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Bibliographic Details
Main Authors: Michelle R Koenig, Ann M Mitzey, Terry K Morgan, Xiankun Zeng, Heather A Simmons, Andres Mejia, Fernanda Leyva Jaimes, Logan T Keding, Chelsea M Crooks, Andrea M Weiler, Ellie K Bohm, Matthew T Aliota, Thomas C Friedrich, Emma L Mohr, Thaddeus G Golos
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2023-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0284964

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https://doi.org/10.1371/journal.pone.0284964

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