CD98 Heavy Chain Is a Potent Positive Regulator of CD4+ T Cell Proliferation and Interferon-γ Production In Vivo.

CD98 Heavy Chain Is a Potent Positive Regulator of CD4+ T Cell Proliferation and Interferon-γ Production In Vivo.

Upon their recognition of antigens presented by the MHC, T cell proliferation is vital for clonal expansion and the acquisition of effector functions, which are essential for mounting adaptive immune responses. The CD98 heavy chain (CD98hc, Slc3a2) plays a crucial role in the proliferation of both C...

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Bibliographic Details
Main Authors: Takeshi Kurihara, Hideki Arimochi, Zaied Ahmed Bhuyan, Chieko Ishifune, Hideki Tsumura, Morihiro Ito, Yasuhiko Ito, Akiko Kitamura, Yoichi Maekawa, Koji Yasutomo
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4596652?pdf=render

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http://europepmc.org/articles/PMC4596652?pdf=render

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