Immunization of chickens with Newcastle disease virus expressing H5 hemagglutinin protects against highly pathogenic H5N1 avian influenza viruses.

Immunization of chickens with Newcastle disease virus expressing H5 hemagglutinin protects against highly pathogenic H5N1 avian influenza viruses.

Highly-pathogenic avian influenza virus (HPAIV) and Newcastle disease virus (NDV) are the two most important poultry viruses in the world. Natural low-virulence NDV strains have been used as vaccines over the past 70 years with proven track records. We have previously developed a reverse genetics sy...

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Bibliographic Details
Main Authors: Baibaswata Nayak, Subrat N Rout, Sachin Kumar, Mohammed S Khalil, Moustafa M Fouda, Luay E Ahmed, Kenneth C Earhart, Daniel R Perez, Peter L Collins, Siba K Samal
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-08-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2716524?pdf=render

Internet

http://europepmc.org/articles/PMC2716524?pdf=render

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