Orphan Toxin OrtT (YdcX) of Escherichia coli Reduces Growth during the Stringent Response

Toxin/antitoxin (TA) systems are nearly universal in prokaryotes; toxins are paired with antitoxins which inactivate them until the toxins are utilized. Here we explore whether toxins may function alone; i.e., whether a toxin which lacks a corresponding antitoxin (orphan toxin) is physiologically re...

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Bibliographic Details
Main Authors: Sabina Islam, Michael J. Benedik, Thomas K. Wood
Format: Article
Language:English
Published: MDPI AG 2015-01-01
Series:Toxins
Subjects:
Online Access:http://www.mdpi.com/2072-6651/7/2/299