Salmonella enterica serovar Typhi plasmid pR ST98 enhances intracellular bacterial growth and S. typhi-induced macrophage cell death by suppressing autophagy

Salmonella enterica serovar Typhi plasmid pR ST98 enhances intracellular bacterial growth and S. typhi-induced macrophage cell death by suppressing autophagy

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OBJECTIVES: Plasmid pR ST98 is a hybrid resistance-virulence plasmid isolated from Salmonella enterica serovar Typhi (S. typhi). Previous studies demonstrated that pR ST98 could enhance the virulence of its host bacteria. However, the mechanism of pR ST98-increased bacterial virulence is still not f...

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Bibliographic Details
Main Authors: Peiyan He, Shuyan Wu, Yuanyuan Chu, Yanru Yang, Yuanyuan Li, Rui Huang
Format: Article
Language:English
Published: Elsevier
Series:Brazilian Journal of Infectious Diseases
Subjects:
plasmid pR ST98
macrophage
autophagy
intracellular bacterial growth
cell death
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702012000300008&lng=en&tlng=en

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702012000300008&lng=en&tlng=en

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