Elucidating the role of EPPK1 in lung adenocarcinoma development

Elucidating the role of EPPK1 in lung adenocarcinoma development

Abstract Background We recently found that epiplakin 1 (EPPK1) alterations were present in 12% of lung adenocarcinoma (LUAD) cases and were associated with a poor prognosis in early-stage LUAD when combined with other molecular alterations. This study aimed to identify a probable crucial role for EP...

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Bibliographic Details
Main Authors: Ken Arimura, Michael Kammer, S. M. Jamshedur Rahman, Chen Sheau-Chiann, Shilin Zhao, Chen Heidi, Rosana Eisenberg, Yong Zou, Sanja Antic, Bradley Richmond, Etsuko Tagaya, Eric Grogan, Pierre Massion, Fabien Maldonado
Format: Article
Language:English
Published: BMC 2024-04-01
Series:BMC Cancer
Subjects:
CRISPR-Cas9
Epiplakin 1
Epithelial-to-mesenchymal transition
MYC/p53 pathway
Online Access:https://doi.org/10.1186/s12885-024-12185-x

Internet

https://doi.org/10.1186/s12885-024-12185-x

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