The SEM-4 Transcription Factor Is Required for Regulation of the Oxidative Stress Response in Caenorhabditis elegans

The SEM-4 Transcription Factor Is Required for Regulation of the Oxidative Stress Response in Caenorhabditis elegans

Oxidative stress causes damage to cells by creating reactive oxygen species (ROS) and the overproduction of ROS have been linked to the onset of premature aging. We previously found that a brap-2 (BRCA1 associated protein 2) mutant significantly increases the expression of phase II detoxification en...

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Bibliographic Details
Main Authors: Adilya Rafikova, Queenie Hu, Terrance J. Kubiseski
Format: Article
Language:English
Published: Oxford University Press 2020-09-01
Series:G3: Genes, Genomes, Genetics
Subjects:
caenorhabditis elegans (c. elegans)
oxidative stress
genetics
gene expression
transcription factor
sem-4
splat-like (sall) family of transcription factors
Online Access:http://g3journal.org/lookup/doi/10.1534/g3.120.401316

Internet

http://g3journal.org/lookup/doi/10.1534/g3.120.401316

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