Intracellular Redox-Balance Involvement in Temozolomide Resistance-Related Molecular Mechanisms in Glioblastoma

Intracellular Redox-Balance Involvement in Temozolomide Resistance-Related Molecular Mechanisms in Glioblastoma

Glioblastoma (GBM) is the most common astrocytic-derived brain tumor in adults, characterized by a poor prognosis mainly due to the resistance to the available therapy. The study of mitochondria-derived oxidative stress, and of the biological events that orbit around it, might help in the comprehens...

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Bibliographic Details
Main Authors: Alessia Lo Dico, Daniela Salvatore, Cristina Martelli, Dario Ronchi, Cecilia Diceglie, Giovanni Lucignani, Luisa Ottobrini
Format: Article
Language:English
Published: MDPI AG 2019-10-01
Series:Cells
Subjects:
oxidative stress
chaperone mediated autophagy (cma)
mitochondrial scavenger
drug resistance
reactive oxygen species (ros), cell motility
Online Access:https://www.mdpi.com/2073-4409/8/11/1315

Internet

https://www.mdpi.com/2073-4409/8/11/1315

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