Intracellular Redox-Balance Involvement in Temozolomide Resistance-Related Molecular Mechanisms in Glioblastoma
Glioblastoma (GBM) is the most common astrocytic-derived brain tumor in adults, characterized by a poor prognosis mainly due to the resistance to the available therapy. The study of mitochondria-derived oxidative stress, and of the biological events that orbit around it, might help in the comprehens...
Main Authors: | Alessia Lo Dico, Daniela Salvatore, Cristina Martelli, Dario Ronchi, Cecilia Diceglie, Giovanni Lucignani, Luisa Ottobrini |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2019-10-01
|
Series: | Cells |
Subjects: | |
Online Access: | https://www.mdpi.com/2073-4409/8/11/1315 |
Similar Items
-
Hypoxia-Inducible Factor-1α Activity as a Switch for Glioblastoma Responsiveness to Temozolomide
by: Alessia Lo Dico, et al.
Published: (2018-07-01) -
CMA mediates resistance in breast cancer models
by: Alessia Lo Dico, et al.
Published: (2023-07-01) -
The Multifaceted Role of CMA in Glioma: Enemy or Ally?
by: Alessia Lo Dico, et al.
Published: (2021-02-01) -
Palmitic and Stearic Acids Inhibit Chaperone-Mediated Autophagy (CMA) in POMC-like Neurons In Vitro
by: Rodrigo Espinosa, et al.
Published: (2022-03-01) -
Chaperone-Mediated Autophagy and Its Emerging Role in Hematological Malignancies
by: Guillaume Robert, et al.
Published: (2019-10-01)