The Bioactivity of Xylene, Pyridine, and Pyrazole Aza Macrocycles against Three Representative <i>Leishmania</i> Species

The Bioactivity of Xylene, Pyridine, and Pyrazole Aza Macrocycles against Three Representative <i>Leishmania</i> Species

Due to the urgent need for finding effective and free of secondary effect treatments for every clinical form of Leishmaniasis, a series of synthetic xylene, pyridine and, pyrazole azamacrocycles were tested against three <i>Leishmania</i> species. A total of 14 compounds were tested agai...

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Bibliographic Details
Main Authors: Álvaro Martín-Montes, Álvaro Martínez-Camarena, Alberto Lopera, Irene Bonastre-Sabater, M. Paz Clares, Begoña Verdejo, Enrique García-España, Clotilde Marín
Format: Article
Language:English
Published: MDPI AG 2023-03-01
Series:Pharmaceutics
Subjects:
<i>Leishmania</i>
chemotherapy
pyridine
pyrazole
macrocycles
mechanism of action
Online Access:https://www.mdpi.com/1999-4923/15/3/992

Internet

https://www.mdpi.com/1999-4923/15/3/992

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