Gut microbiota-mediated secondary bile acids regulate dendritic cells to attenuate autoimmune uveitis through TGR5 signaling

Gut microbiota-mediated secondary bile acids regulate dendritic cells to attenuate autoimmune uveitis through TGR5 signaling

Summary: Gut microbiota-mediated secondary bile acids (BAs) play an important role in energy balance and host metabolism via G protein-coupled receptors and/or nuclear receptors. Emerging evidence suggests that BAs are important for maintaining innate immune responses via these receptors. However, t...

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Bibliographic Details
Main Authors: Jianping Hu, Chaokui Wang, Xinyue Huang, Shenglan Yi, Su Pan, Yiting Zhang, Gangxiang Yuan, Qingfeng Cao, Xingsheng Ye, Hong Li
Format: Article
Language:English
Published: Elsevier 2021-09-01
Series:Cell Reports
Subjects:
uveitis
bile acids
dendritic cells
autoimmune disease
TGR5
Online Access:http://www.sciencedirect.com/science/article/pii/S221112472101175X

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http://www.sciencedirect.com/science/article/pii/S221112472101175X

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