Activation of AMPK-PGC-1α pathway ameliorates peritoneal dialysis related peritoneal fibrosis in mice by enhancing mitochondrial biogenesis

Activation of AMPK-PGC-1α pathway ameliorates peritoneal dialysis related peritoneal fibrosis in mice by enhancing mitochondrial biogenesis

Background The pathogenesis of peritoneal dialysis (PD)-related peritoneal fibrosis (PF) is not clearly understood, and current treatment options are limited.Methods In this study, the effect of PD-related PF on mitochondrial biogenesis was investigated, and the effect of activation of the adenosine...

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Bibliographic Details
Main Authors: Jun Wu, Jushuang Li, Baohong Feng, Zhimin Bi, Geli Zhu, Yanxia Zhang, Xiangyou Li
Format: Article
Language:English
Published: Taylor & Francis Group 2022-12-01
Series:Renal Failure
Subjects:
Peritoneal dialysis
peritoneal fibrosis
mitochondrial biogenesis
AMPK
PGC-1α
Online Access:https://www.tandfonline.com/doi/10.1080/0886022X.2022.2126789

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https://www.tandfonline.com/doi/10.1080/0886022X.2022.2126789

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