Oxidative insult can induce malaria-protective trait of sickle and fetal erythrocytes

Oxidative insult can induce malaria-protective trait of sickle and fetal erythrocytes

Carriers of haemoglobinopathies are protected from severe malaria, likely due to reduced surface expression of virulence factors. Here, Cyrklaff et al. show that, similar to haemoglobinopathies, a transient oxidative insult affects actin reorganization and mitigates the development of cerebral malar...

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Bibliographic Details
Main Authors: Marek Cyrklaff, Sirikamol Srismith, Britta Nyboer, Kvetoslava Burda, Angelika Hoffmann, Felix Lasitschka, Sophie Adjalley, Cyrille Bisseye, Jacques Simpore, Ann-Kristin Mueller, Cecilia P. Sanchez, Friedrich Frischknecht, Michael Lanzer
Format: Article
Language:English
Published: Nature Portfolio 2016-11-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/ncomms13401

Internet

https://doi.org/10.1038/ncomms13401

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